A Level Biology AQA

This subject is broken down into 106 topics in 11 modules:

  1. Handling data 13 topics
  2. Required practicals 12 topics
  3. Biological Molecules 10 topics
  4. Cells 12 topics
  5. Exchange and Transport Systems 10 topics
  6. Genetic Information, Variation, and Relationships Between Organisms 9 topics
  7. Energy Transfers In and Between Organisms 8 topics
  8. Organism Changes in their Environments 11 topics
  9. Genetics, Populations, Evolution, and Ecoosystems 10 topics
  10. The Control of Gene Expression 6 topics
  11. Using Genome Projects 5 topics
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  • 11
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  • 106
    topics
  • 40,237
    words of revision content
  • 5+
    hours of audio lessons

This page was last modified on 9 January 2025.

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Biology

Handling data

Planning Investigations: Hypothesis Formation

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Planning Investigations: Hypothesis Formation

Formation of Hypothesis

  • A hypothesis is a clear, concise, and testable statement that expresses the expected outcome or prediction for a scientific investigation.
  • An effective hypothesis should be based on prior knowledge or observation.
  • Hypotheses are often stated as an “If…, then…” statement that predicts the effect of one variable on another.
  • The independent variable is the factor that is manipulated or changed during an experiment, while the dependent variable is the factor that is measured.
  • Hypothesis should express a cause and effect relationship between the independent and dependent variables.
  • The hypothesis is not the end result; rather, it guides the data collection and analysis phase of the research project.

Characteristics of a Valid Hypothesis

  • It must be a testable statement—one that can give rise to measurable outcomes.
  • It should identify and relate the independent and dependent variables clearly.
  • It needs to be based on existing scientific knowledge.
  • It should be simple and specific, using precise terminology.
  • A valid hypothesis often predicts the anticipated direction of the effect.

Importance of Null Hypothesis

  • The null hypothesis (H0) states that there is no relationship or effect of the independent variable on the dependent variable in the investigated population.
  • It represents a statement of no difference or no association between variables and serves as the basis of comparison for testing the alternative hypothesis.
  • The aim is not necessarily to prove the null hypothesis correct, but to determine whether it can be rejected or not rejected based on the evidence collected.

Alternative Hypothesis

  • The alternative hypothesis (H1 or Ha) is the rival claim to the null hypothesis that we believe might be true instead.
  • It proposes that there is a significant interaction or relationship between the variables studied.
  • It is evaluated based on the end results; if the results provide enough evidence against the null hypothesis, the alternative hypothesis is deemed more likely.

Course material for Biology, module Handling data, topic Planning Investigations: Hypothesis Formation

Biology

Exchange and Transport Systems

Digestion and Absorption

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Digestion and Absorption

Understanding Digestion and Absorption

  • Digestion is the process by which food is broken down into small, soluble molecules that can be absorbed into the bloodstream.
  • This process involves both mechanical digestion (chewing and churning in the stomach) and chemical digestion (the action of enzymes).

The Digestive System

  • The digestive system encompasses a series of organs, predominantly the mouth, oesophagus, stomach, small intestine and large intestine, which together process food into nutrients.
  • Salivary glands in the mouth produce saliva, which contains the amylase enzyme that begins carbohydrate digestion.
  • The oesophagus connects the mouth and the stomach, and food is moved along by peristalsis, a wave-like muscle contraction.
  • The stomach performs mechanical digestion through muscular contractions, and its gastric juice provides the acidic environment for pepsin to break down proteins.
  • The small intestine is the main site for digestion and absorption. It is lined with villi and microvilli that greatly increase surface area for maximum nutrient absorption.
  • The large intestine reabsorbs water and certain vitamins, forming semi-solid faeces which are subsequently excreted.

Role of Enzymes in Digestion

  • Enzymes play a crucial role in digestion, each efficiently breaking down specific nutrients into simpler molecules.
  • Amylase, found in the mouth and the small intestine, breaks down starch into maltose.
  • Proteases, such as pepsin in the stomach and trypsin in the small intestine, split proteins into amino acids.
  • Lipases in the small intestine convert triglycerides (fats and oils) into glycerol and fatty acids.

Absorption of Nutrients

  • The absorption process occurs predominantly within the small intestine where nutrients pass from the lumen of the intestine into the bloodstream.
  • Different nutrients are absorbed via different mechanisms. For example, glucose and amino acids are transported by active transport, whereas fatty acids and glycerol enter epithelial cells by simple diffusion.
  • The resulting absorption of water, salts, vitamins and minerals facilitates the circulation and use of these nutrients throughout the body.

Implications of Dietary Choices

  • An individual’s diet impacts their health and can lead to conditions such as malnutrition or obesity.
  • A balanced diet includes appropriate proportions of carbs, proteins, and fats, along with necessary vitamins, minerals and water.

Remember, understanding the intricacies of digestion and absorption underscores the significance of a balanced diet for overall health and wellbeing. It is essential to appreciate how nutrients we consume are meticulously converted into forms that the body can use to function and sustain life.

Course material for Biology, module Exchange and Transport Systems, topic Digestion and Absorption

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