GCSE Biology (Triple) Edexcel

This subject is broken down into 75 topics in 9 modules:

  1. Key Concepts in Biology 8 topics
  2. Cells and Control 7 topics
  3. Genetics 10 topics
  4. Natural Selection and Genetic Modification 9 topics
  5. Health, Disease and the Development of Medicines 10 topics
  6. Plant Structures and their Functions 6 topics
  7. Animal Coordination, Control and Homeostasis 8 topics
  8. Exchange and Transport in Animals 6 topics
  9. Ecosystems and Material Cycles 11 topics
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  • 9
    modules
  • 75
    topics
  • 26,784
    words of revision content
  • 3+
    hours of audio lessons

This page was last modified on 28 September 2024.

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Biology (Triple)

Key Concepts in Biology

Key Concepts: Cells

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Key Concepts: Cells

Key Concepts: Cells

Types and Structures of Cells

  • Understand that all living organisms are composed of cells. There are two main types of cells: prokaryotic (found in bacteria and archaea) and eukaryotic (found in plants, animals, fungi, and protists).
  • Recognise the basic structure of animal and plant cells. Common structures include the nucleus, cytoplasm, cell membrane, mitochondria, and ribosome. Plant cells also have a cell wall, chloroplasts, and a large central vacuole.

Functions and Specialisations of Cells

  • Learn the functions of the different cell structures. For example, the nucleus contains the cell's genetic material, the mitochondria are responsible for energy production, and the cell membrane controls the movement of substances in and out of the cell.
  • Appreciate the concept of cell specialisation. Different types of cells have different roles within an organism. For instance, a nerve cell's structure allows it to transmit electrical signals, while a red blood cell's structure enables it to carry oxygen.

Cell Life Cycle and Division

  • Understand the life cycle of a cell, also known as the cell cycle. This includes interphase (where the cell grows and prepares for division), mitosis (where the cell divides its nucleus and contents), and cytokinesis (where the cell splits into two).
  • Familiarise oneself with the process of cell division. Mitosis produces two identical daughter cells for growth or to replace cells that have been damaged or died. In contrast, meiosis produces four non-identical cells for sexual reproduction.

Substances Movement in Cells

  • Study the basic principles of diffusion, osmosis, and active transport. These are three ways substances can move in or out of cells. Diffusion is the movement from a high to low concentration, osmosis involves the movement of water, and active transport requires energy to move substances against the concentration gradient.

Stem Cells and Enzymes

  • Comprehend the concept of stem cells and their potential applications. Stem cells are unspecialised cells that have the ability to become any type of cell in the body. This capacity makes them valuable in medical research and treatment.
  • Explore the function and importance of enzymes in cellular processes. Enzymes are biological catalysts which speed up chemical reactions in cells.

Genetic Material in Cells

  • Grasp the basic principles of DNA, genes, and chromosomes. DNA carries the genetic information in the form of genes. These are located on chromosomes in the cell nucleus. Learn about how genetic information is used to make proteins and how mutations can lead to different characteristics or conditions.

Course material for Biology (Triple), module Key Concepts in Biology, topic Key Concepts: Cells

Biology (Triple)

Health, Disease and the Development of Medicines

Health, Disease and Medicines: Memory Lymphocytes and Immunisation

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Health, Disease and Medicines: Memory Lymphocytes and Immunisation

Understanding Memory Lymphocytes

  • Memory lymphocytes are a key part of the body's immune response. They can remember pathogens the body has been exposed to before, allowing a quicker response if the same pathogen is encountered again.
  • These types of white blood cells originate in the bone marrow as B and T lymphocytes. If they encounter an antigen which fits their specific antigen receptor, they become activated and start to multiply rapidly.
  • Some of these activated B and T lymphocytes become plasma cells that produce antibodies to fight the infection. Others become memory B and T cells, which can respond more effectively to future infections by the same pathogen.
  • Memory lymphocytes ensure the body's response is not just faster but also stronger on subsequent exposures to the same pathogen, such is the case with immunisation. This is called the secondary immune response.

The Immunisation Process

  • During an immunisation, a vaccine is introduced into the body. This vaccine contains either harmless parts of, or the dead or inactive form of, a pathogen.
  • Vaccines stimulate an immune response, but they do not cause disease. This is because the pathogen(s) they contain are not able to cause an outbreak of the disease.
  • Immunisation leads to the creation of memory lymphocytes which remember how to fight that specific pathogen. This is how vaccines provide immunity.
  • If the actual pathogen enters the body after vaccination, the corresponding memory cells trigger a fast and vigorous immune response, often eliminating the pathogen before the onset of symptoms.

Resulting Immunity and Vaccine Impact

  • Herd immunity occurs when a large portion of a community becomes immune to a disease, reducing the likelihood of it spreading. This is achieved through mass immunisation.
  • Some diseases have been effectively eradicated through global immunisation efforts, such as smallpox. Others, like measles and polio, have been greatly reduced.
  • Concerns and controversies such as vaccine safety, ethics, and disinformation can affect immunisation rates and therefore impact herd immunity.

Development of Medicines and Treatments

  • Changes in treatment and in the development of medicines over time have reduced deaths from infection and increased life expectancy. Vaccines have played a significant role in this progress.

Course material for Biology (Triple), module Health, Disease and the Development of Medicines, topic Health, Disease and Medicines: Memory Lymphocytes and Immunisation

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