Biotechnology and genetic engineering
Understanding Biotechnology and Genetic Engineering
- Biotechnology is the use of living systems and organisms to develop or make products, it encompasses techniques for modifying living organisms according to human purposes.
- Genetic engineering is the direct manipulation of an organism's genes using biotechnology. It involves the addition, removal or alteration of genetic material.
- Genetic engineering techniques include recombinant DNA technology, gene cloning and gene therapy.
- CRISPR-Cas9 is a sophisticated genetic engineering technique that can accurately add, delete or modify genes.
Applications and Benefits of Biotechnological Techniques
- Medical field: genetic engineering has potential use in creating personalised medicines, producing insulin for diabetic patients and the development of gene therapy for genetic disorders.
- Agriculture: biotechnology can be used to create GM crops resistant to pests, diseases, and harsh environmental conditions, enhancing food security.
- Environmental science: biotechnology can help in waste management through bioremediation, the process of using organisms to neutralize pollutants.
Ethical and Moral Considerations
- The issue of 'playing God' arises with genetic modification, especially with technologies like gene editing in human embryos, leading to designer babies.
- Equity issues: Biotechnology advancements might only be accessible to the affluent, creating a socio-economic divide.
- Ownership and patenting of life forms is another major ethical issue, as it can lead to monopolization and exploitation.
- Biotechnology might be used for malicious purposes, for example, in creating bioweapons.
Risks and Criticisms of Biotechnology and Genetic Engineering
- The risk of creating unintended mutations which could have unpredictable impacts on the environment and human health.
- Concerns about the long-term effects of consuming GM foods, as the health impacts are still not completely understood.
- Genetically modified organisms (GMOs) could potentially crossbreed with natural organisms, impacting ecosystems.
- Biotechnology industries may prioritize profit over potential ecological or health risks.
Legislation and Regulatory Bodies
- The Human Fertilisation and Embryology Authority (HFEA) oversees the use of pre-embryonic stages of human embryos for research or treatment in the UK.
- The European Food Safety Authority (EFSA) provides scientific advice and communication on existing and emerging risks in relation to genetically modified organisms (GMOs).
- International ethical guidelines such as the Nuremberg Code and Declaration of Helsinki guide human experimentation including genetic manipulation.
- In the USA, the Food and Drug Administration (FDA) regulates the release of genetically engineered organisms.